casestudy/pharm/physio8

A 75-year-old woman with long-standing hypertension and angina due to coronary heart disease presents with ankle edema, nocturia, increased shortness of breath with activity, and a chronic nonproductive cough. Her blood pressure is 170/80 and her heart rate 92. Electrocardiography and chest radiography indicate the presence of left ventricular hypertrophy.
Relate the presence of uncontrolled hypertension and coronary artery disease to the development of heart failure in this woman.
Explain the significance of left ventricular hypertrophy in terms of both a compensatory mechanism and a pathologic mechanism in the progression of heart failure.

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